Mosesetjane is a village situated northwest of Mokopane town in the Mogalakwena Local Municipality within the Waterberg District Municipality of the Limpopo Province of South Africa.
The village is divided into three sections under three chiefs: Chief Kekana of the Kgobudi section, Chief Frans Ledwaba of the Sekgoboko section, and Chief N Lebelo of the Mmalepetleke area.
The population is multiethnic. The dominant languages in the area are Sumayela Ndebele and Northern Sotho.
This village shares boundaries with the following villages to the east and far east: Tshamahansi, Ga-Magongoa, and Ga-Mokaba. To the south Mosesetjane is boarded by Masodi, Moshate, and Ga-Madiba. Sandsloot, Mapela, and the Mogalakwena Platinum Mine are found to the north of this village.
This agriculture-rich village has a state-of-the-art clinic based in the Sekgoboko Zone 2 area, which caters for the entire village; the clinic is conveniently situated next to the road that passes through the village to Mapela Village. Economically, the area is boosted by the neighbouring Mogalakwena Platinum Mine (formerly Potgitersrust Platinum Limited Mine), which employs many members of the community. In recent years, the area has seen an influx of immigrants attracted by the platinum mine.
